Variations in complete blood count, in pre and post haemodialysis patients of chronic renal failure

Abstract

Objective: To determine variations in complete blood count (CBC), in pre and post hemodialysis patients of chronic renal failure

Methodology: This cross-sectional study was conducted in the physiology department and data were collected from urology department I at Liaquat university Hospital Hyderabad from April 2021 to September 2021. Patients with chronic kidney disease between the ages of 18 and 50 underwent hemodialysis of either gender. Blood samples were taken before the dialysis with anticoagulant and serum tubes for hematological investigations such as RBCs, hemoglobin, WBCs and platelets. After dialysis blood samples were re-taken with anticoagulant and serum tubes for hematological investigations. Hematological parameters were compared to see the hematological alteration pre and post dialysis. Chronic kidney disease was evaluated as per operational definition. All the data were entered in the proforma. All the data were entered into SPSS 26.0 version.

Results: A total of 167 patients were studied, for the assessment of hematological parameters and vitamin B12 in pre- and post-dialysis. The mean age of the patients was 43.23+12.90 years. Males were 61.1%, and females were 38.9%.  Average duration of dialysis was 13.40+2.88 months. As per pre- and post-hematological parameters the hemoglobin level was statistically significant, while RBC, WBC and platelets were statically insignificant (p->0.05).

Conclusion: As per the study conclusion, the hematological parameters, were observed improved significantly after dialysis.